Pain Home > Pentazocine

Pentazocine is a liquid that is injected into a vein, muscle, or just under the skin. It is prescribed to treat moderate-to-severe pain, and for use before surgery or in combination with anesthesia. This medicine is a type of controlled substance, meaning it does have a potential for abuse. This pain reliever is typically given every three or four hours. Side effects include dizziness, nausea, and vomiting.

What Is Pentazocine?

Pentazocine lactate (Talwin®) is a prescription pain medication approved to treat moderate-to-severe pain. It may also be used before surgery or in combination with anesthesia (medication that puts you to sleep during surgery).
 
Pentazocine is an injectable opioid pain medication. It used to be available in an oral form, which was taken by mouth, but this form is no longer available. Currently, oral pentazocine is only available as a combination product, which means it and another medication are together in one tablet.
 
Talwin® Nx (pentazocine/naloxone) contains pentazocine in combination with naloxone (Narcan®). The medication is a tablet that is taken by mouth. Naloxone is added to the drug to help prevent it from being misused via injection. Pentazocine is also available as a tablet in combination with acetaminophen (Talacen®).
 
Pentazocine is considered a Schedule IV controlled substance. Controlled substances are medications whose possession and use are strictly regulated because of their potential for abuse. Schedule IV controlled substances have a low potential for abuse compared with Schedule II controlled substances, such as morphine, or Schedule III products, such as hydrocodone/APAP.
 
(Click What Is Pentazocine Used For? for more information on this topic, including possible off-label uses.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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