ConZip capsules are specially designed to release the medication continuously over a 24-hour period. The active ingredient, tramadol, is classified as a "centrally acting opioid analgesic." This means that it works in the central nervous system (the brain and spinal cord), acts much like morphine in the body, and relieves pain. ConZip binds to certain opioid receptors in the body known as μ ("mu") receptors.
ConZip also works in a similar way as some antidepressant medications by inhibiting the reuptake of certain brain chemicals (serotonin and norepinephrine). Serotonin and norepinephrine are two of several chemicals used to send messages from one nerve cell to another.
As a message travels down a nerve, it causes the end of the cell to release serotonin or norepinephrine. The serotonin or norepinephrine enters the gap between the first nerve cell and the one next to it. When enough serotonin or norepinephrine reaches the second nerve cell, it activates receptors on the cell and the message continues on its way. The first cell then quickly absorbs any serotonin or norepinephrine that remains in the gap between cells. This is called "reuptake."
Is It Safe for Children to Use ConZip?
ConZip is not approved for use in children and is not recommended for use in this age group (defined as anyone younger than 18 years old).
Off-Label ConZip Uses
On occasion, healthcare providers may recommend medications for something other than the officially approved uses. This is called an "off-label" use. There are no universally accepted off-label uses for ConZip at this time.
U.S. Drug Enforcement Administration. Schedules of controlled substances: placement of tramadol into Schedule IV (July 2, 2014). DEA Web site. Available at: http://www.deadiversion.usdoj.gov/fed_regs/rules/2014/fr0702.htm. Accessed September 28, 2014.
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