Pain Home > Drug Interactions With Children's Acetaminophen

A number of medications may potentially cause drug interactions with children's acetaminophen, including warfarin, phenobarbital, and carbamazepine. These drugs may affect the way the body handles children's acetaminophen, which can decrease the effectiveness of the medicines and increase the risk of side effects. Children's acetaminophen interactions may also occur if the drug is taken with other products containing acetaminophen.

Children's Acetaminophen Drug Interactions: An Overview

Children's acetaminophen (Children's Tylenol®) can potentially interact with several other medications. However, many of these medications are not usually used in children. Some of the medicines that are used in children that may lead to children's acetaminophen interactions include:
  • Carbamazepine (Carbatrol®, Epitol™, Equetro®, Tegretol®)
  • Codeine and acetaminophen (Capital® and Codeine, Phenco-Care™, Tylagesic™, Acetaminophen No. 3, Acetaminophen No. 4)
  • Isoniazid (Nydrazid®)
  • Phenobarbital (Luminal®)
  • Several non-prescription cough, cold, flu, and allergy products
  • Warfarin (Coumadin®, Jantoven®).
(For a more complete list of medications that interact with acetaminophen, including medications that are not likely to be taken by children, see Drug Interactions With Acetaminophen.)

Children's Acetaminophen Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when children's acetaminophen is combined with any of the drugs listed above.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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