Pain Home > Acetaminophen Dosage

For regular and extra-strength doses of acetaminophen, recommendations typically start at two tablets every four to six hours as needed. If you are taking the extended-release version, it is recommended that you take two tablets every eight hours. For children ages 6 to 12, the suggested dose is one regular-strength tablet every four to six hours as needed.

(In November 2010, the United States Food and Drug Administration approved an intravenous form of acetaminophen. For information on this product, see Ofirmev.)

Dosing With Acetaminophen: An Introduction

The dosage of acetaminophen (Tylenol®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your age
  • The particular acetaminophen product
  • Other medications you may be taking
  • Other medical conditions you may have.
As is always the case, do not adjust this amount unless your healthcare provider specifically instructs you to do so.

Acetaminophen Dosages for Adults and Older Children

These acetaminophen dosing instructions apply to adults and children age 12 and older (see Children's Tylenol Dosage and Infant Tylenol Dosage for information about younger children). The amount recommended depends on which acetaminophen product you are using.
For adults and children age 12 and older, the recommended dose is as follows:
  • Regular-strength (325 mg) acetaminophen: Two tablets every four to six hours as needed, not to exceed 12 tablets in 24 hours
  • Extra-strength (500 mg) acetaminophen: Two tablets (or geltabs) every four to six hours as needed, not to exceed 8 tablets in 24 hours
  • Extended-release (650 mg) acetaminophen: Two tablets (or geltabs) every eight hours, not to exceed six tablets in 24 hours
  • Liquid acetaminophen (500 mg per 15 mL): Two tablespoons (30 mL total) every four to six hours as needed, not to exceed eight tablespoonfuls in 24 hours.
It is important to avoid taking more than 4 grams (4000 mg) of acetaminophen per day. This includes other sources of acetaminophen, including many prescription pain medications and many nonprescription cold and cough remedies.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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