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Lodine is a nonsteroidal anti-inflammatory drug that is commonly prescribed to relieve pain, swelling, inflammation, and stiffness associated with arthritis and other painful conditions. The medication is available in tablet or capsule form and comes in a variety of strengths, including 200 mg capsules, 300 mg capsules, 400 mg tablets, and 500 mg tablets. Potential side effects include nausea, dizziness, and heartburn or indigestion.

What Is Lodine?

Lodine® (etodolac) is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). The drug is used to reduce pain, inflammation, swelling, and stiffness caused by several conditions.

Who Makes Lodine?

Brand-name Lodine was manufactured by Wyeth Pharmaceuticals but is no longer being made. Generic versions are still available.

What Is It Used For?

Lodine has been licensed for the following uses:
  • Pain relief, such as for pain following a medical procedure, from muscle strain, or caused by inflammation in a tendon (tendonitis) or bursa (bursitis)
  • Relief of osteoarthritis symptoms, including pain, stiffness, and swelling
  • Relief of rheumatoid arthritis symptoms.
Lodine is not a cure for these types of arthritis, however, nor does it slow down the progression of the disease.
(Click What Is Lodine Used For? for more information, including possible off-label uses.)

How Does It Work?

Lodine and other NSAIDs work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.
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Lodine (Etodolac)

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