Lodine Side Effects

Some people may experience adverse effects with the use of Lodine. Side effects that are reported the most often include gas, fatigue, and diarrhea. Potentially serious side effects may also occur, requiring immediate medical attention, such as congestive heart failure, severe bleeding problems, and stomach problems. Fortunately, side effects of Lodine are usually minor and easily treated.

 

An Introduction to Lodine Side Effects

As with any medicine, side effects are possible with Lodine® (etodolac), but not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. In clinical studies, up to 10 percent of people stopped taking Lodine because of side effects.
 
(This article covers many, but not all, of the possible side effects with Lodine. Your healthcare provider can discuss a more complete list of Lodine side effects with you.)
 

Common Side Effects of Lodine

Lodine has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to those that occurred in a similar group of people not taking the drug. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
 
Based on these studies, the most common Lodine side effects (occurring in more than 3 percent of people) included:
 
  • Heartburn or indigestion (dyspepsia)
  • Stomach pain
  • Diarrhea
  • Gas
  • Nausea
  • Dizziness
  • Tiredness or weakness.
     
Other side effects with Lodine, occurring in more than 1 percent of people and thought to be related to the drug, included but were not limited to:
 
  • Constipation
  • Unexplained bleeding
  • Black, tarry stools
  • Changes in stools
  • Vomiting
  • Anemia
  • Fatigue
  • Depression
  • Nervousness
  • Pain with urination (dysuria)
  • Increased need to urinate
  • Itching
  • Unexplained rash
  • Ringing in the ears (tinnitus)
  • Blurred vision.
     
(Lodine Side Effects Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;