Serious Ketoprofen Side Effects
As with any drug, there is the potential for serious side effects with
ketoprofen. The U.S. Food and Drug Administration (FDA) warns that people using ketoprofen or other non-steroidal anti-inflammatory drugs (
NSAIDs), with the exception of aspirin, may have a higher risk of having a
heart attack or
stroke than those who do not take NSAIDs. This risk may be higher in people who have been taking NSAIDs for a long time. These events can occur without any warning and can lead to loss of life. Get emergency medical help as soon as possible if you experience any of the following symptoms:
- Chest pain
- Shortness of breath
- Weakness on one part of your body
- Slurred speech.
Other rare ketoprofen side effects include but are not limited to:
- Allergic reactions, such as:
- Swelling of the face or body
- Blisters
- Unexplained skin rash
- Wheezing
- Difficulty breathing
- Stomach or intestine problems, including bleeding, ulcers, or a hole (known as a perforation)
- Liver damage, which can cause:
- Nausea
- Fatigue
- Yellowing of the skin or whites of the eyes (jaundice)
- Excessive tiredness
Because ketoprofen can increase the risks for major or life-threatening bleeding, contact your healthcare provider immediately if you notice any unusual bleeding or have any of the following symptoms:
- Bloody nose
- Black, tarry stools
- Blood in the urine or stools
- Vomiting blood
- Red or purple spots on the skin (purpura).