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Precautions and Warnings With Infant Acetaminophen

There are many precautions and warnings with infant acetaminophen to be aware of before giving your child the drug. For example, it is important to know that the medicine may cause liver damage. You should not give your child infant acetaminophen if he or she is allergic to any components of the medication.

Infant Acetaminophen: What Should I Tell My Healthcare Provider?

You should talk with your child's healthcare provider prior to using infant acetaminophen (Infants' Tylenol®) if your child has:
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • G6PD deficiency
  • Any allergies, including allergies to food, dyes, or preservatives.
Make sure to tell your child's healthcare provider about all other medicines your child is taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Warnings and Precautions for Infant Acetaminophen

Warnings and precautions to be aware of prior to giving your child infant acetaminophen include the following:
  • Infant acetaminophen can damage the liver. Therefore, if your child already has liver problems, you should talk to your child's healthcare provider before using infant acetaminophen.
  • Infant acetaminophen contains sodium benzoate, an inactive ingredient that can cause serious problems if given in large quantities to newborns (especially premature or low birth weight newborns). Talk to your child's healthcare provider before using infant acetaminophen in newborns.
  • Infant acetaminophen can interact with other medications (see Infant Acetaminophen Drug Interactions for more information).
  • You should not treat your child for a fever for more than three days or pain for more than five days without talking with your child's healthcare provider. Your child may have a serious problem that requires medical attention. Also, contact your child's healthcare provider if your child's pain or fever gets worse or if swelling is present.
  • Let your child's healthcare provider know if your child has a sore throat that is severe, lasts more than two days, or is accompanied by a fever, headache, rash, nausea, or vomiting.
  • Infant acetaminophen may increase the risk of serious problems in people with G6PD deficiency (a low amount of a certain enzyme in the body). If your child has a G6PD deficiency, talk to his or her healthcare provider before using infant acetaminophen.
  • Some children who are allergic to salicylates (such as aspirin) may also be allergic to infant acetaminophen. However, many children with such allergies can take infant acetaminophen without any problems.
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