Infant Acetaminophen Drug Interactions

Carbamazepine, phenobarbital, and many over-the-counter cough or cold products can potentially interact with infant acetaminophen. Drug interactions may occur that could lead to side effects or complications, such as liver damage. Other non-prescription medications containing acetaminophen may also cause drug interactions with infant acetaminophen.

Infant Acetaminophen Drug Interactions: An Overview

Infant acetaminophen (Concentrated Tylenol® Infants' Drops) can potentially interact with other medications. However, many of these medications are not usually used by young children. Some of the children's medicines that may lead to infant acetaminophen drug interactions include:
 

Infant Acetaminophen Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when infant acetaminophen is combined with any of the drugs listed above.
 
Carbamazepine (Carbatrol, Epitol, Equetro, Tegretol)
Carbamazepine can affect the way the body handles infant acetaminophen, making both drugs less effective and more toxic. Talk to your child's healthcare provider about using infant acetaminophen drops in children who take carbamazepine.
 
Codeine and Acetaminophen (Capital and Codeine, Phenco-Care, Tylagesic, Acetaminophen No. 3, Acetaminophen No. 4)
In general, you should avoid giving your child infant acetaminophen if he or she is taking codeine and acetaminophen products, as you may give your child too much acetaminophen.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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