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Indocin Precautions and Warnings

Some Indocin Precautions and Warnings

Some Indocin warnings and precautions to be aware of include the following:
 
  • There are certain other medications with which Indocin may interact (see Indocin Drug Interactions).
     
  • All NSAIDs, including Indocin, have been reported to cause cardiovascular events such as a heart attack or stroke, which can result in loss of life. People with cardiovascular disease or who have cardiovascular risk factors appear to be at greater risk. To decrease your chances of experiencing these problems, take the smallest effective dose for the shortest period of time. Also, call 911 if you notice things such as chest pain, shortness of breath, weakness, and slurring of speech.
 
  • All NSAIDs, including Indocin, may cause or worsen high blood pressure. If you have high pressure, tell your healthcare provider before you start taking Indocin. Should your healthcare provider choose to prescribe Indocin, he or she may wish to use particular caution.
     
  • All NSAIDs, including Indocin, may cause congestive heart failure or swelling. Make sure to contact your healthcare provider if you notice unexplained weight gain or swelling. Also, Indocin should be used with caution in people with heart failure.
     
  • All NSAIDs, including Indocin, have been reported to cause problems in the stomach and intestines, including bleeding (known as gastrointestinal bleeding), stomach ulcers, or holes in the stomach or intestines. These problems can lead to serious complications or even loss of life. If you have a history of ulcers or gastrointestinal bleeding, it's extremely important that you tell your healthcare provider before taking Indocin. He or she will likely need to use extreme caution when prescribing Indocin in your case. To decrease the chances of these problems occurring, take the smallest effective dose for the shortest period of time. Make sure to contact your healthcare provider immediately if you experience any signs or symptoms of stomach ulcers or bleeding, including:
o Abdominal pain (or stomach pain)
o Indigestion
o Black, tarry stools
o Vomiting blood.
  • Kidney damage can occur in people taking NSAIDs, including Indocin. It is more common in people with kidney disease, heart failure, liver problems, those taking diuretics or ACE inhibitor medication, and the elderly.
     
  • Liver damage can occur in people who are taking Indocin. Contact your healthcare provider immediately if you notice things such as nausea, tiredness, lethargy, itchy or yellowing skin, abdominal pain (or stomach pain), or flu-like symptoms.
     
  • NSAIDs, including Indocin, have been reported to cause allergic reactions. Seek emergency medical attention immediately if you notice things such as difficulty breathing and swelling of the face and throat.
     
  • In rare cases, people taking Indocin can develop a very serious rash. If you notice an unexplained rash or blisters, fever, or itchy skin, stop taking the Indocin and call your healthcare provider.
     
  • If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting Indocin. Alcohol can affect the way the liver works, indirectly affecting the Indocin.
     
  • NSAIDs have been known to cause an increase in liver enzymes. Therefore, your healthcare provider may recommend that you have a blood test that assesses your liver function before starting Indocin and 12 weeks after treatment has started.
     
  • Indocin may cause anemia. If you are taking Indocin for an extended amount of time and show signs of anemia, tell your healthcare provider.
     
  • Some people who have taken Indocin for long periods of time have experienced problems with their eyes. These include deposits in the cornea and problems with the macula. These problems can cause the vision to blur. If you develop blurred vision while taking Indocin, let your healthcare provider know right away.
     
  • In people with depression or other psychiatric problems, such as bipolar disorder or schizophrenia, Indocin may worsen these conditions. People with epilepsy or Parkinson's disease may also experience a worsening of their condition. Let your healthcare provider know if any of your symptoms seem to worsen while you are taking Indocin.
     
  • Indocin can cause drowsiness in some people, especially when starting the medication or when the Indocin dosage is changed. Therefore, make sure that you know how your body reacts to Indocin before driving a car, operating heavy machinery, or performing any tasks that require mental alertness.
     
  • You should not take Indocin with any other NSAIDs as this may increase your risk for any of the problems discussed above. There are many NSAIDs available with or without a prescription; make sure to read labels carefully. Some examples of NSAIDs include ibuprofen (Motrin®, Advil®), naproxen (Aleve®, Anaprox®, Naprosyn®, and Naprelan®), celecoxib (Celebrex®), etodolac (Lodine®, Lodine XL), diclofenac (Cataflam®, Voltaren®), and meloxicam (Mobic®). Ask your doctor or pharmacist for a complete list of these medications.
     
  • Indocin is a pregnancy Category C medicine, meaning that Indocin could potentially cause harm to your unborn child. If you are pregnant, you should only take Indocin if the benefit outweighs the possible risk to your unborn child. Women in their third trimester of pregnancy should not take Indocin because it can cause injury and even death to the developing fetus. If you become pregnant while taking Indocin, contact your healthcare provider immediately (see Indocin and Pregnancy for more information).
     
  • If you are nursing, you should not take Indocin. In the event that you are nursing and taking Indocin, talk to your healthcare provider about whether to stop nursing or discontinue the medicine.
     
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Indocin Medication

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