Indocin Drug Interactions

Potential Indocin drug interactions may occur involving medications such as warfarin, lithium, cyclosporine, and methotrexate. In addition, taking other nonsteroidal anti-inflammatory drugs with Indocin can result can lead to potentially dangerous drug interactions. When certain medicines are taken together with Indocin, drug interactions may increase the risk of developing serious health problems, such as major bleeding, stomach ulcers, and kidney damage.

Indocin Drug Interactions: An Introduction

Indocin® (indomethacin) has a number of medicines with which it may interact. Some of these potential Indocin drug interactions involve medications such as:
 
 
  • Angiotensin II receptor blockers (ARBs), such as:

 

 
 
 
  • Corticosteroids, including (but not limited to):
     
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
 
 
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
 
 
 
Several herbal and nutritional supplements can also interact with Indocin and may increase the risk of bleeding. Examples of these include (but are not limited to):
 
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Indocin Medication

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