More Detail on Indocin Interactions
Other Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Using these pain relievers with
Indocin can increase the risk for bleeding. Generally,
acetaminophen (
Tylenol®) products can be used safely with Indocin.
Warfarin (Coumadin, Jantoven)
If you are taking blood thinners, such as warfarin, while taking Indocin, your body may metabolize them differently than intended. You healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust your dosages accordingly. INR and prothrombin time are tests used to measure how well your blood is clotting.
Aspirin
Studies have indicated that when aspirin and Indocin are used together, the chances are higher for stomach ulcers or other problems in
digestive system. Aspirin has also been shown to decrease the levels of Indocin in the blood. Talk to your healthcare provider about using Indocin and aspirin together in your particular situation.
ACE Inhibitors (Accupril, Lotensin, Vasotec, Altace, Zestril, Prinivil, Monopril, Capoten)
Indocin may inhibit the
blood pressure-lowering effects of ACE inhibitors. Your healthcare provider may need to adjust your dose of these drugs.
Beta Blockers
Indocin may inhibit the blood pressure-lowering effects of beta blockers. Your healthcare provider may need to adjust your dose of these drugs.
Diuretics (Torsemide [Demadex], Furosemide [Lasix], Hydrochlorothiazide)
Indocin may reduce the activity of diuretics. Your healthcare provider may need to adjust your dose of these drugs.
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
Taking Indocin and
lithium together may increase the levels of lithium in your body by decreasing the kidneys' ability to remove lithium. Your healthcare provider may need to adjust your dose of these drugs and monitor the level of lithium in your blood.
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