Hydrocodone/APAP and Breastfeeding

According to the manufacturers' recommendations for hydrocodone/APAP, breastfeeding women should not take this drug. The acetaminophen component (APAP) does pass through breast milk; however, it should not cause problems for a nursing infant. It is unknown if the hydrocodone component (a narcotic) passes through breast milk. If it does, it's likely to cause significant problems in breastfeeding infants.

 

Hydrocodone/APAP While Breastfeeding: An Overview

It is unknown if hydrocodone/APAP (hydrocodone and acetaminophen) is safe for use by breastfeeding women. If you are breastfeeding or are thinking about breastfeeding, talk with your healthcare provider before taking hydrocodone/APAP. The manufacturers of these products do not recommend that women use such products while breastfeeding.
 

Hydrocodone/APAP and Breastfeeding: What Does the Research Say?

Hydrocodone/APAP contains two different medications: hydrocodone bitartrate (a narcotic) and acetaminophen (Tylenol®, also known as APAP). The acetaminophen component does pass through breast milk, but it is not likely to cause problems (see Tylenol and Breastfeeding). However, no studies have been done to see if the hydrocodone component also passes through breast milk in women. As a narcotic, hydrocodone could cause significant problems in a nursing infant if it does pass through.
 

Talking With Your Healthcare Provider About Hydrocodone/APAP and Breastfeeding

You should talk with your healthcare provider about hydrocodone/APAP and breastfeeding. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision about hydrocodone/APAP and breastfeeding that is right for you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;