Fibromyalgia Medications

There is currently only one drug approved as a specific fibromyalgia medication. However, several drugs approved for other purposes can be used "off-label" to treat some of the symptoms of fibromyalgia. In addition, a few experimental drugs are currently being tested to see if they can become safe and effective medications for fibromyalgia.

 

An Overview of Fibromyalgia Medications

There are several treatment options for a person diagnosed with fibromyalgia. One treatment option is medication. At present, only one medication (Lyrica®) has been approved by the U.S. Food and Drug Administration (FDA) specifically for treating fibromyalgia. Healthcare providers may also treat fibromyalgia with a variety of medications developed and approved for other purposes. Using these medicines for the treatment of fibromyalgia is known as using them for an "off-label" purpose. While these drugs have not been licensed to treat fibromyalgia, a number of studies have shown how they can provide benefits to people with the condition.
 
(Click Off-Label to learn about what off-label means, as well as off-label rules and how it is important to talk with your healthcare provider about the benefits and risks of using a drug off-label.)
 
The following are some of the most commonly used categories of medications for fibromyalgia:
 
  • Pain relievers (analgesics)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Antidepressants
  • Benzodiazepines
  • Antiseizure medicines
  • A select group of other medications used to treat specific symptoms.

 

(Fibromyalgia Medications Continued: Page 2)
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD