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Fentanyl Buccal Tablets Dosage

Maintenance Dose

Once an effective dosing is established, your healthcare provider will prescribe the appropriate strength that will allow you to use only one fentanyl buccal tablet for each episode of breakthrough pain. If, on occasion, your pain is not relieved after 30 minutes, you may use one additional tablet. You must then wait at least four hours before taking another dosage for breakthrough pain.
If you have several consecutive breakthrough pain episodes that require two doses for adequate relief, your healthcare provider may choose to increase your dosage. If you experience more than four episodes of breakthrough pain each day, your healthcare provider may choose to increase your maintenance (around-the-clock) opioid dosage.

General Information on Taking Fentanyl Buccal Tablets

Some considerations for people to keep in mind during treatment with this drug include the following:
  • This medication comes in the form of a tablet, which is dissolved in the mouth between the upper cheek and gums (above a rear molar tooth). Alternatively, the tablet may be placed under the tongue.
  • Keep the tablet between your cheek and gum (or under the tongue) until it dissolves. This normally takes 14 to 25 minutes. You may swallow any remaining tablet with a glass of water after 30 minutes.
  • Fentanyl buccal tablets come in a sealed blister package, which should not be opened until immediately before use. To open the blister package, peel the foil backing away to expose the tablet. Do not try to push the tablet through the foil, as this may damage the tablet.
  • Do not cut, crush, or break the tablets. They must be placed in the mouth whole.
  • Do not suck on, chew, or swallow the tablets. Doing so may cause less of the medication to be absorbed by the body, resulting in inadequate pain relief.
  • Place fentanyl buccal tablets on alternating sides of your mouth with each subsequent dosage.
  • If you feel dizzy, unusually sleepy, or sick to your stomach before the tablet is completely dissolved, rinse your mouth with water and spit the tablet into the sink or toilet. Make sure to rinse the sink or flush the toilet to dispose of fentanyl buccal tablets (see Fentora Storage and Disposal for information about safe disposal).
  • Continue to take your regularly scheduled, around-the-clock, opioid pain medication while taking fentanyl buccal tablets. The tablets alone will not control your pain.
  • This medication may be very dangerous, and could even cause death, if ingested by a child or someone for whom the medication is not prescribed. Store fentanyl buccal tablets in a safe place, out of the reach of children (see Fentora Storage and Disposal for more information).
  • For the medication to work properly, it must be taken as prescribed. Do not increase your dose or suddenly stop using this medication without your healthcare provider's approval.
  • If you are unsure about anything related to your fentanyl tablet dosage, please talk with your healthcare provider or pharmacist.
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Fentanyl Buccal Tablet Information

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