Feldene

Feldene is a prescription medication that has been licensed to treat signs and symptoms of osteoarthritis and rheumatoid arthritis. Pain, inflammation, swelling, and stiffness are among the symptoms that Feldene relieves. The drug works by inhibiting the action of certain hormones that cause inflammation and pain in the body. It is important to note that Feldene does not cure these conditions or slow their progression. Common side effects of this medication include heartburn, diarrhea, and stomach pain.

 

What Is Feldene?

Feldene® (piroxicam) is a prescription medicine used to treat pain, inflammation, swelling, and/or stiffness. It is part of a class of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs for short.
 

Who Makes Feldene?

Feldene is manufactured by Pfizer.
 

What Is Feldene Used For?

Feldene has been licensed for the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis.
 
Feldene is not a cure for the types of arthritis mentioned above, nor does it slow the progression of the disease.
 
(Click What Is Feldene Used For? for more information on these uses, as well as possible off-label uses for Feldene.)
 

How Does Feldene Work?

Feldene and other NSAIDs work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.
 

Feldene Effects

By blocking the effects of prostaglandins, Feldene is useful for reducing pain, inflammation, and joint swelling associated with different forms of arthritis and painful conditions.
 

Feldene: When and How Do I Take It?

Some general considerations for when and how to take Feldene include:
 
  • Feldene comes in a capsule form. It is taken by mouth.
     
  • Your Feldene dosage should be taken with a glass of water. Taking it with milk or food may prevent an upset stomach.
     
  • Do not break, chew, or crush the Feldene capsules.
     
  • For osteoarthritis and rheumatoid arthritis, it may take several weeks for Feldene to begin working to its full potential.
     
  • It is important to take the lowest effective dose for the least amount of time in order to treat your condition. This will reduce the risks of serious side effects.
     
  • Feldene should be taken at the same time each day to maintain an even level of the drug in your blood.
     
  • For Feldene to work properly, you have to take it as prescribed. Feldene will not work if you take it in a way other than the way your healthcare provider prescribes.
     

Feldene Dosing

The dose of Feldene your healthcare provider recommends will vary depending on a number of factors, including:
 
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you may be currently taking.
     
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Feldene Dosage for more information about dosing for Feldene.)
 

Side Effects of Feldene

(The Feldene side effects listed below are NOT a complete list of possible side effects with this drug. Your healthcare provider can discuss a more complete list of these side effects with you.)
 
As with any medicine, there are possible side effects with Feldene. Not everyone who takes Feldene will experience Feldene side effects. When side effects do occur, in many cases they are minor, meaning that they require no treatment or are easily treated by your healthcare provider.
 
Common side effects with Feldene include, but are not limited to:
 
  • Heartburn or indigestion (dyspepsia)
  • Swelling
  • Stomach pain
  • Diarrhea
  • Elevated liver enzymes
  • Gas
  • Unexplained bleeding
  • Ulcer in the stomach or intestines (peptic ulcer)
  • Anemia
  • Nausea
  • Dizziness
  • Headache
  • Tiredness or weakness
  • Unexplained rash
  • Itching
  • Ringing in the ears (tinnitus).
     
Less common but serious side effects include:
 
  • Cardiovascular problems, including a heart attack or stroke
  • Stomach or intestinal problems, including bleeding, ulcers, or a hole (known as a perforation)
  • Liver damage
  • Kidney problems, including kidney failure
  • Fluid retention
  • Congestive heart failure
  • Allergic reaction
  • Unexplained rash.
     
These possible side effects are shared with all NSAIDs and can lead to life-threatening complications or even loss of life.
 
(Click Feldene Side Effects to learn about the specific side effects of Feldene, including possible serious side effects to look out for.)
 

Drug Interactions With Feldene

Feldene can potentially interact with a number of medicines.
 
(Click Feldene Drug Interactions for more information about Feldene and these other medicines.)
 

Feldene: What Should I Tell My Healthcare Provider?

The U.S. Food and Drug Administration (FDA) warns that people using NSAIDs, including Feldene, may have a higher risk of having a heart attack or stroke than those people who do not take NSAIDs. This warning does not apply to those who take aspirin. This risk may be higher in people who have been taking NSAIDs for a long time. These events can occur without any warning and can lead to death. Be sure to tell your doctor if you have or have ever had any of the following:
 
You should also talk with your healthcare provider prior to taking Feldene if you have:
 
  • Asthma
  • Congestive heart failure
  • Liver disease or liver failure
  • Kidney disease or kidney failure
  • Bleeding problems (or if you are taking medicine that decreases the ability of blood to clot)
  • Diabetes
  • Stomach ulcers, stomach bleeding, or a history of either condition
  • Any allergies to medicines, including aspirin or other NSAID pain medicines.
     
Let your healthcare provider know if you:
 
  • Are pregnant or thinking about becoming pregnant (see Feldene and Pregnancy)
  • Are breastfeeding
  • Drink alcohol frequently
  • Smoke
  • Are having or have recently had heart surgery.
     
Also, tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Feldene Precautions and Warnings for more information on this topic, including information on who should not take Feldene.)
 

Feldene Overdose

People who take too much Feldene may have overdose symptoms that could include, but are not limited to:
 
  • Bleeding
  • Nausea
  • Vomiting
  • Stomach pain
  • Excessive sleepiness
  • Coma
  • Convulsions
  • The heart stopping.
     
If you happen to overdose on Feldene, seek medical attention immediately.
 

Feldene: Storage Methods

Feldene should be stored at room temperature in a dry place. Feldene capsules should be kept in an airtight container.
 
Keep Feldene and all medications out of the reach of children.
 

Feldene: What Should I Do If I Miss a Dose?

If you do not take your Feldene as scheduled, take your next dose as soon as you remember. If it is close to the next scheduled dose, skip the missed one and continue with normal dosing. Never take a double dose!
 

Feldene: Strengths

Feldene is available in several strengths, including:
 
  • Feldene 10 mg capsules
  • Feldene 20 mg capsules.
     

Generic Feldene

There is a generic form of Feldene available.
 
(Click Generic Feldene for more information.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;