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Exalgo Side Effects

Potentially serious side effects of Exalgo include seizures, severe constipation, or difficulty breathing. In most cases, however, people tolerate the medication quite well and any problems that occur are typically easy to treat. Common side effects include constipation, nausea, and drowsiness. Other, less common reactions include fever, anxiety, and weight loss.

An Introduction to Exalgo Side Effects

Just like any medicine, Exalgo™ (hydromorphone ER) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Exalgo. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Exalgo

Exalgo has been studied thoroughly in clinical trials. Some of these studies compared Exalgo to a placebo (a "sugar pill" with no active ingredients), while others did not.
In these studies, the most common side effects seen with Exalgo included:
  • Constipation (see Exalgo and Constipation) -- in up to 31 percent of people
  • Nausea -- up to 28 percent
  • Drowsiness -- up to 15 percent
  • Vomiting -- up to 14 percent
  • Headaches -- up to 12 percent
  • General weakness -- up to 11 percent
  • Dizziness -- up to 11 percent.
Other common reactions (occurring in 1 to 10 percent of people) included:
  • Itching
  • Insomnia
  • Diarrhea
  • Dry mouth
  • Water retention/swelling in the hands or feet
  • Sweating
  • Loss of appetite
  • Joint pain
  • Abdominal pain (stomach pain)
  • Muscle spasms
  • Weight loss
  • Anxiety
  • Back pain
  • Indigestion or heartburn
  • Depression
  • Shortness of breath
  • Muscle spasms
  • Fever
  • Chest discomfort.
Due to the way the data was reported, it is difficult to know if many of these side effects are actually due to Exalgo or are the result of unrelated factors.
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Exalgo Medication Information

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