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Exalgo Dosage

Different factors will affect the dose of Exalgo you are prescribed, such as how you respond to Exalgo, other medical conditions you may have, and the type and dose of other painkillers you have taken. This product comes in tablet form and is taken by mouth once a day. It is not meant to be taken on an "as needed" basis.

An Introduction to Dosing for Exalgo

The dose of Exalgo™ (hydromorphone ER) your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to Exalgo
  • The type and dose of other painkillers you have taken
  • The type and severity of your pain
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Exalgo Dosage for Pain

In clinical studies, the amounts used ranged from 8 mg up to 64 mg daily. The starting dose of Exalgo your healthcare provider recommends will depend mostly on the amount and type of painkillers you were previously taking.
For immediate-release oral hydromorphone, a straight mg-per-mg conversion is recommended. Simply add up the total mg of hydromorphone you take per day -- this is the recommended total Exalgo daily dose, given as a single amount per day.
If you are switching from any nonhydromorphone painkillers or from injected hydromorphone, your healthcare provider will need to convert your current dosage to an appropriate Exalgo dosage. It is often best to slightly underestimate the dose initially rather than overestimate in order to avoid dangerous Exalgo side effects.
Your healthcare provider may also recommend a "rescue" medication (a short-acting painkiller) to use in addition to Exalgo for times when your pain is especially severe (known as "breakthrough pain," as it breaks through your baseline, long-acting painkiller). A rescue medication can be especially useful when you are first starting Exalgo, as many healthcare providers underestimate your initial hydromorphone requirement in order to avoid dangerous side effects.
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Exalgo Medication Information

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