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Precautions and Warnings With Etodolac Extended-Release

Some Precautions and Warnings With Etodolac Extended-Release

Patients should be aware of the following warnings and precautions for this drug:
 
To decrease the chances of these problems occurring, it is recommended that people take the smallest effective dose for the shortest period of time. Also, call 911 or an ambulance if you notice things such as chest pain, shortness of breath, weakness, and slurring of speech.
  • All NSAIDs, including etodolac extended-release, may worsen high blood pressure or cause high blood pressure. Etodolac extended-release should be used with caution in people with known high blood pressure.
     
  • All NSAIDs, including etodolac extended-release, may cause congestive heart failure or swelling. Make sure to contact your healthcare provider if you notice unexplained weight gain or swelling. Also, etodolac extended-release should be used with caution in people with heart failure.
     
  • All NSAIDs, including etodolac extended-release, have been reported to cause problems in the stomach and intestines, including bleeding (known as gastrointestinal bleeding), stomach ulcers, or holes in the stomach or intestines. These problems can lead to serious complications or even loss of life. Extreme caution should be used if etodolac extended-release is prescribed for people with a history of ulcers or gastrointestinal bleeding.
To decrease the chances of these problems occurring, it is recommended that people take the smallest effective dose for the shortest period of time. Make sure to contact your healthcare provider immediately if you experience any signs or symptoms of stomach ulcers or bleeding, including:
o Stomach pain
o Indigestion
o Black, tarry stools
o Vomiting blood.
  • Kidney damage can occur in people taking NSAIDs, including etodolac extended-release. It is more common in people with kidney disease, heart failure, liver problems, those taking diuretics or ACE inhibitor medication, and the elderly.
     
  • Liver damage can happen with people who are taking etodolac extended-release. Contact your healthcare provider immediately if you notice things such as nausea, tiredness, lethargy, itchy or yellowing skin, abdominal pain, or flu-like symptoms.
     
  • NSAIDs, including etodolac extended-release, have been reported to cause allergic reactions. Seek emergency medical attention immediately if you notice things such as difficulty breathing and swelling of the face and throat.
     
  • In rare cases, people taking etodolac extended-release can develop a very serious rash. If you notice an unexplained rash or blisters, fever, or itchy skin, stop taking the etodolac extended-release and call your healthcare provider.
     
  • If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting etodolac extended-release. Alcohol can affect the way the liver works, indirectly affecting the etodolac extended-release.
     
  • NSAIDS have been known to cause an increase in liver enzymes. Therefore, it is recommended that you have a blood test that looks at your liver function before starting etodolac extended-release and 12 weeks after treatment has started.
     
  • Etodolac extended-release has been known to cause anemia. If you are taking etodolac extended-release for an extended amount of time and show signs of anemia, talk to your healthcare provider.
     
  • You should not take etodolac extended-release with any other NSAIDs, because this may increase your risk for any of the problems discussed above. There are many NSAIDs available with or without a prescription; make sure to read labels carefully. Some examples of NSAIDs are ibuprofen (Motrin®, Advil®), naproxen (Aleve®, Anaprox®, Naprosyn® and Naprelan®), celecoxib (Celebrex®), ketoprofen (Orudis®, Oruvail®), meloxicam (Mobic®), diclofenac (Cataflam®, Voltaren®), and others. You can ask your doctor or pharmacist for a complete list of these medications.
     
  • Etodolac extended-release is a pregnancy Category C medicine, meaning that it could potentially cause harm to your unborn child. If you are pregnant, you should take etodolac extended-release only if the benefit outweighs the possible risk to your unborn child. This drug is not recommended for women in their third trimester of pregnancy because it can cause injury (and even death) to the developing fetus. If you become pregnant while taking etodolac extended-release, contact your healthcare provider immediately (see Lodine XL and Pregnancy for more information).
     
  • If you are nursing, it is recommended that you do not take etodolac extended-release. Therefore, if you are taking etodolac extended-release, discuss with your healthcare provider whether to stop nursing or discontinue the medicine.
     
8 Frequent Pain Syndromes

Etodolac Extended-Release Medicine

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