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Drug Interactions With Etodolac Extended-Release

More Details About Etodolac Extended-Release Drug Interactions

The following sections explain in detail how the drugs mentioned above can cause potentially negative interactions when combined with etodolac extended-release.
 
ACE Inhibitors
Combining etodolac extended-release with an ACE inhibitor can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the ACE inhibitor for lowering blood pressure.
 
ARBs
Combining etodolac extended-release with an ARB can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the ARB for lowering blood pressure.
 
Beta Blockers
Combining etodolac extended-release with a beta blocker may interfere with the beta blocker's ability to lower blood pressure. Check with your healthcare provider before taking these medications together.
 
Bile Acid Sequestrants
Bile acid sequestrants can bind to etodolac extended-release in the digestive tract and delay its absorption into the body. To avoid this drug interaction, etodolac extended-release should be taken at least one hour before or four to six hours after the bile acid sequestrant has been taken.
 
Corticosteroids
Using corticosteroids with etodolac extended-release can increase the risk of bleeding. Your healthcare provider may choose to monitor you more closely or adjust your dose of these drugs.
 
Cyclosporine
Etodolac extended-release may increase the level of cyclosporine in the blood, increasing the risk of serious cyclosporine side effects. In addition, this combination may increase the risk of kidney damage. Check with your healthcare provider before taking these medications together.
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