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Duragesic Drug Interactions

Pegvisomant
Duragesic may decrease the effectiveness of pegvisomant. If you take these medications together, your healthcare provider may need to increase your pegvisomant dose.
 
Thiazide Diuretics
Using Duragesic with a thiazide diuretic may increase your risk for orthostatic hypotension, which is a decrease in blood pressure when you stand up. Talk to your healthcare provider if you notice symptoms of orthostatic hypotension, such as faintness, dizziness, and lightheadedness, if you take these medications together.
 

Final Thoughts

It is possible that not all drug interactions with Duragesic were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific interactions that may apply to you.
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