Dosing With Diclofenac Sodium (Cont.)

Dosing With Diclofenac Sodium for Ankylosing Spondylitis

The recommended starting dosage of diclofenac sodium for most people with ankylosing spondylitis is 25 mg, four times a day. If needed, another 25 mg of diclofenac sodium may be taken at bedtime.
 

General Information on Dosing With Diclofenac Sodium

Considerations for people taking diclofenac sodium include the following:
 
  • It may take several weeks for the full effects of diclofenac sodium to be felt.
     
  • Your diclofenac sodium dosage should be taken with a glass of water. Taking it with milk or food may prevent upset stomach.
     
  • Do not break, chew, or crush the diclofenac sodium tablets.
     
  • It is important to take the lowest effective dose for the least amount of time in order to treat your condition. This will decrease the risk of serious side effects.
     
  • Diclofenac sodium should be taken at the same time each day to maintain an even level of the drug in your blood.
     
  • For diclofenac sodium to work properly, you have to take it as prescribed. Diclofenac sodium will not work if you take it in a way other than how your healthcare provider recommends.
     
  • If you do not take your diclofenac sodium as scheduled, take your next dose as soon as you remember. If it is close to the next scheduled dose, skip the missed one and continue with normal dosing. Do not take double the dose or combine your dose with other NSAIDs (nonsteroidal anti-inflammatory drugs). It is okay to take it with acetaminophen (Tylenol®), however.
     
  • The strengths of diclofenac sodium, diclofenac sodium extended-release, Cataflam® (diclofenac potassium), and their generic forms differ, even if the strength is the same in milligrams.
     
  • If you are unsure about anything related to diclofenac sodium, including dosing with diclofenac sodium, talk to your doctor, nurse, or pharmacist. Do not stop taking diclofenac sodium without first discussing it with your healthcare provider.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;