Diclofenac potassium has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and usually compared to those taking a placebo (a "sugar pill" with no active ingredients). This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group taking the placebo.
Based on these studies, the most common
diclofenac potassium side effects include:
- Abdominal pain (or stomach pain)
- Constipation
- Diarrhea
- Heartburn or indigestion (dyspepsia)
- Gas
- Unexplained bleeding
- An ulcer in the stomach or intestines (peptic ulcer)
- Nausea
- Vomiting
- Anemia
- Dizziness
- Swelling
- An increase in liver enzymes
- Headache
- Itching
- Unexplained rash
- Ringing in the ears (tinnitus).
During clinical studies, there were also some side effects that occurred rarely in people taking diclofenac potassium. These side effects generally occurred in less than 1 percent of people. It is difficult to tell whether these side effects were actually caused by the medication or something else. These possible diclofenac potassium side effects include but are not limited to: