Side Effects of Diclofenac Potassium (Cont.)

Serious Side Effects of Diclofenac Potassium

As with any drug, there is the potential for serious side effects with diclofenac potassium. The U.S. Food and Drug Administration (FDA) warns that people using NSAIDs, including diclofenac potassium, may have a higher risk of having a heart attack or stroke than those people who do not take NSAIDs. This warning does not apply to those who take aspirin. This risk may be higher in people who have been taking NSAIDs for a long time. These events can occur without any warning and can lead to loss of life. Get emergency medical help by calling 911 as soon as possible if you experience any of the following symptoms:
 
  • Chest pain
  • Shortness of breath
  • Weakness on one part of your body
  • Slurred speech.
     
Other possible serious diclofenac potassium side effects include but are not limited to:
 
  • Allergic reactions, such as swelling of the face or body, blisters, unexplained skin rash, wheezing, or difficultly breathing
  • Stomach or intestinal problems, including bleeding, ulcers, or a hole (known as a perforation)
  • Liver damage, which can cause nausea, fatigue, yellowing of the skin or white of the eyes, and excessive tiredness
  • Kidney problems, including kidney failure
  • Fluid retention or unexplained weight gain
  • Congestive heart failure
  • Sensation that the pill is stuck in your throat.
     
Because diclofenac potassium can increase the risk of major or life-threatening bleeding, contact your doctor immediately if you notice any unusual bleeding or have any of the following symptoms:
 
  • Bloody nose
  • Black, tarry stools
  • Blood in the urine or stools
  • Vomiting blood
  • Red or purple spots on the skin.
     
(Side Effects of Diclofenac Potassium Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;