Pain Channel
Topics & Medications
Related Channels

Drug Interactions With Diclofenac Potassium

CYP 2C9 Inhibitors
The liver breaks down (metabolizes) this medication using certain enzymes known as CYP 2C9 enzymes. Several other medications, known as CYP 2C9 inhibitors, slow down these enzymes, potentially causing diclofenac potassium to build up in the bloodstream, perhaps increasing the risk of side effects. Check with your healthcare provider before taking such medications together.
Diclofenac potassium may increase the level of digoxin in your bloodstream, increasing the risk of dangerous digoxin side effects. If you are taking digoxin, check with your healthcare provider before starting or stopping diclofenac potassium.
Combining diclofenac potassium with a diuretic can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the diuretic.
Taking diclofenac potassium and lithium together may increase the levels of lithium in your body by reducing the kidneys' ability to remove lithium. Your healthcare provider may need to adjust your dose of these drugs and monitor the level of lithium in your blood.
"Blood Thinners" and Other Similar Drugs
Combining diclofenac potassium with anticoagulants ("blood thinners"), antiplatelet drugs, or other medications that increase the risk of bleeding may lead to serious bleeding problems, including dangerous internal bleeding. Do not combine diclofenac potassium with such medications without your healthcare provider's approval and supervision.
Diclofenac potassium may increase the risk of methotrexate toxicity. Do not combine these medications without your healthcare provider's supervision and approval.
8 Frequent Pain Syndromes

Diclofenac Potassium (Cataflam)

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2020 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.