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Drug Interactions With Diclofenac/Misoprostol

More Information on Drug Interactions With Diclofenac/Misoprostol

The following sections explain in detail the potentially negative interactions that can occur when diclofenac/misoprostol is combined with any of the drugs listed above.
 
ACE Inhibitors
Diclofenac/misoprostol may decrease the effectiveness of ACE inhibitors in lowering blood pressure. Taking these medicines together may also decrease kidney function. Your healthcare provider will need to monitor you more closely if you take these medicines together.
 
ARBs
Diclofenac/misoprostol may decrease the effectiveness of ARBs in lowering blood pressure. Taking these medicines together may also decrease kidney function. Your healthcare provider will need to monitor you more closely if you take these medicines together.
 
Beta Blockers
Taking diclofenac/misoprostol in combination with a beta blocker may decrease the effectiveness of the beta blocker in lowering blood pressure. Your healthcare provider may need to monitor your blood pressure more closely if you take these medicines together.
 
Bile Acid Sequestrants
Bile acid sequestrants can interfere with the absorption of diclofenac/misoprostol from the digestive tract. If you are taking both diclofenac/misoprostol and a bile acid sequestrant, try to separate the doses of these two medicines by at least two hours to minimize the risk of this interaction.
 
Certain Antacids
Taking diclofenac/misoprostol with antacids that contain magnesium can increase the risk for diarrhea. If you need an antacid during diclofenac/misoprostol treatment, make sure to take one that does not contain magnesium. Your pharmacist can help you choose a magnesium-free antacid.
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Diclofenac/Misoprostol Information

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