In November 2010, the United States Food and Drug Administration (FDA) withdrew all medications that contain propoxyphene from the market. It has been determined that the risks of propoxyphene outweigh the possible benefits. In particular, the FDA was concerned about the drug's ability to cause serious changes in the heart rhythm, even at normal doses. Pharmacies will no longer sell this medication, and people who take it should stop and ask their healthcare provider for a more suitable pain medication.
Darvocet® (propoxyphene/acetaminophen) is a prescription medicine licensed for the treatment of mild-to-moderate pain. It comes in tablet form and is available in three different strengths:
- Darvocet-N 50 -- 50 mg of propoxyphene napsylate and 325 mg of acetaminophen
- Darvocet-N 100 -- 100 mg of propoxyphene napsylate and 650 mg of acetaminophen
- Darvocet A500 -- 100 mg of propoxyphene napsylate and 500 mg of acetaminophen.
For Darvocet-N 50 and Darvocet-N 100, the recommended dosage is 100 mg of propoxyphene napsylate and 650 mg of acetaminophen (equal to one Darvocet-N 100 tablet or two Darvocet-N 50 tablets) every four hours as needed for pain.
The maximum recommended dosage for Darvocet-N 100 and Darvocet A500 is six tablets per day. For Darvocet-N 50, the maximum recommended dosage is 12 tablets per day.
(Click Darvocet Dosage for more detailed information on when and how to take Darvocet and to find out what you should be aware of before using this pain medication.)