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Precautions and Warnings With Cyclobenzaprine ER

You should talk to your healthcare provider about the precautions and warnings with cyclobenzaprine ER to help ensure safe treatment. It is also important to tell him or her if you have any existing conditions, including glaucoma, liver disease, or any allergies. You may not be able to take cyclobenzaprine ER safely if you have congestive heart failure, hyperthyroidism, or arrhythmia.

Cyclobenzaprine ER: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking cyclobenzaprine ER (Amrix®) if you have:
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Warnings and Precautions for Cyclobenzaprine ER

Some warnings and precautions to be aware of prior to taking cyclobenzaprine ER include the following:
 
  • If you have liver disease, your body may not handle cyclobenzaprine ER as well as usual. Cyclobenzaprine ER is not recommended for people with any degree of liver impairment.
     
  • People over age 65 should not take cyclobenzaprine ER, as studies have shown that elderly individuals cannot clear the drug from the body as well as younger individuals.
     
  • Cyclobenzaprine ER commonly causes drowsiness and dizziness, which may interfere with your ability to drive, operate heavy machinery, or focus mentally. Even if you take cyclobenzaprine ER just at bedtime, you may experience a hangover-like effect in the morning.
     
  • Check with your healthcare provider before taking cyclobenzaprine ER if you have glaucoma (an eye condition) or difficulty passing urine, as cyclobenzaprine ER may make these conditions worse.
 
  • Cyclobenzaprine ER may increase the risk of a potentially dangerous group of symptoms known as serotonin syndrome, especially when used in combination with certain other medications. These symptoms include:
    • Confusion
    • Hallucination
    • Fast heartbeat
    • Feeling faint
    • Fever
    • Sweating
    • Muscle spasm
    • Difficulty walking
    • Diarrhea.
 
Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.
 
  • Cyclobenzaprine ER can potentially interact with many other medications (see Drug Interactions With Cyclobenzaprine ER).
     
  • Cyclobenzaprine ER is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not currently known (see Amrix and Pregnancy).
     
  • It is not known if cyclobenzaprine ER passes through breast milk in humans. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Amrix and Breastfeeding).
     
Alternative Therapies for Pain Management

Cyclobenzaprine ER Medication Info

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