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Clinoril Drug Interactions

When medicines such as ACE inhibitors or corticosteroids are taken together with Clinoril, drug interactions may occur. Some interactions may significantly increase the levels of Clinoril in your system; others can cause side effects, such as stomach ulcers, kidney damage, or bleeding. Other medicines that may potentially cause Clinoril drug interactions include methotrexate, probenecid, cyclosporine, and certain herbal or nutritional supplements.

Clinoril Drug Interactions: An Overview

Clinoril® (sulindac) has a number of medicines that it can potentially interact with. Some of these Clinoril drug interactions may include:
  • Angiotensin II receptor blockers (ARBs), such as:


  • Corticosteroids, including (but not limited to):
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
Several herbal and nutritional supplements can also interact with Clinoril and may increase the risk of bleeding. Examples of these include, but are not limited to:
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Clinoril Information

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