Pain Channel
Topics & Medications
Quicklinks
Related Channels

Precautions and Warnings for Celecoxib

Specific Precautions and Warnings for Celecoxib

Precautions and warnings to be aware of prior to taking celecoxib include the following:
 
  • Celecoxib can interact with certain medications (see Drug Interactions With Celecoxib).
     
  • All NSAIDs, including celecoxib, have been linked to cardiovascular events, such as heart attack or stroke, which can result in loss of life. People who have cardiovascular disease or cardiovascular risk factors appear to be at greater risk. To decrease the chances of these problems occurring, you should take the smallest effective dose for the shortest period. Call 911 if you notice things such as:
 
    • Chest pain
    • Shortness of breath
    • Weakness
    • Slurring of speech.
 
  • All NSAIDs may cause high blood pressure or make the condition worse in people who already have it. Thus, celecoxib should be used with caution in people with known high blood pressure.
     
  • All NSAIDs, including celecoxib, may cause congestive heart failure or fluid retention. Contact your healthcare provider if you notice unexplained weight gain or swelling while taking the drug. Celecoxib should be used with caution in people with heart failure.
     
  • All NSAIDs have been reported to cause problems in the stomach and intestines, including bleeding (known as gastrointestinal bleeding), stomach ulcers, or holes in the stomach or intestines (called perforations). These problems can lead to serious complications or even loss of life. Extreme caution should be used if celecoxib is prescribed for people with a history of ulcers or gastrointestinal bleeding. To decrease the risk of these problems, you should take the smallest effective dose for the shortest period. Contact your healthcare provider immediately if you experience any signs or symptoms of stomach ulcers or bleeding, including:
 
    • Stomach pain
    • Indigestion
    • Black, tarry stools
    • Vomiting blood.
     
  • Kidney damage can occur in people taking NSAIDs, including celecoxib. This occurrence is more common in the elderly and in people with kidney disease, heart failure, liver problems, and those taking a diuretic or ACE inhibitor.
     
  • Liver damage can occur in people taking celecoxib. Contact your healthcare provider immediately if you notice things such as:
 
    • Nausea
    • Tiredness
    • Lethargy
    • Itchy or yellowing skin
    • Abdominal pain (stomach pain)
    • Flu-like symptoms.
 
  • NSAIDs, including celecoxib, have been reported to cause allergic reactions. Seek emergency medical attention if you notice things such as difficulty breathing or swelling of the face and throat.
     
  • In rare cases, people taking celecoxib can develop a serious rash. If you notice an unexplained rash or develop blisters, fever, or itchy skin, stop taking celecoxib and call your healthcare provider.
     
  • If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting celecoxib. Both celecoxib and frequent alcohol use increase the risk of gastrointestinal bleeding.
     
  • NSAIDS have been known to cause an increase in liver enzymes. If elevated liver enzymes do not go away or become worse, you should stop taking celecoxib.
     
  • There have been rare cases of anemia possibly linked to celecoxib. If you are taking this drug for an extended period and show signs of anemia, talk to your healthcare provider.
 
  • Celecoxib should be used with caution in children with systemic onset juvenile rheumatoid arthritis, as the medication might increase the risk of disseminated intravascular coagulation (DIC), a potentially fatal condition.
     
  • Celecoxib could make asthma worse, especially in people with aspirin-sensitive asthma.
     
  • You should not take celecoxib with any other NSAID, as this may increase your risk for any of the problems discussed in this article. Many NSAIDs are available without a prescription, so make sure to read all labels carefully. Examples of NSAIDs include:
 
 
  • Celecoxib is a pregnancy Category C or D medicine, depending on the stage of the pregnancy, which means it could potentially harm your unborn child. If you become pregnant while taking this drug, contact your healthcare provider immediately. (Click Celebrex and Pregnancy for more information.) 

 

  • Celecoxib passes through breast milk. Therefore, if you are breastfeeding a child, check with your healthcare provider (or your child's healthcare provider) before taking this medication (see Celebrex and Breastfeeding).
     
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Celecoxib (Celebrex)

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.