Drug Interactions With Celecoxib

Drug interactions with celecoxib can cause an increased risk of stomach ulcers, increased levels of medication in the blood, and decreased effectiveness of certain medications. Some of the drugs that can interact negatively with celecoxib include aspirin, fluconazole, and lithium. If you are experiencing drug interactions with celecoxib, your healthcare provider may adjust your dosages or monitor you more closely.

 

Drug Interactions With Celecoxib: An Introduction

Celecoxib (Celebrex®) can potentially interact with a number of medications. These possible celecoxib drug interactions can include the following:
 

More Information on Interactions With Celecoxib

The following sections explain in detail how the drugs listed above can have a negative effect if taken with celecoxib.
 
ACE Inhibitors
When ACE inhibitors and celecoxib are taken together, the effect of the ACE inhibitor may be reduced. Your healthcare provider may adjust your dose of the ACE inhibitor to avoid this interaction.
 
Aspirin
Aspirin and celecoxib can be used together; however, studies have indicated that the risk of stomach ulcers is higher when these medicines are combined. Talk to your healthcare provider about using aspirin and celecoxib together in your particular situation.
(Drug Interactions With Celecoxib Continued: Page 2)
Add this article to your Favorites     Email this article     Print
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;