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Celecoxib Dosing

Rheumatoid Arthritis
When beginning treatment for rheumatoid arthritis, the typical starting dose is celecoxib 100 mg to 200 mg, twice a day.
Juvenile Rheumatoid Arthritis
Celecoxib is approved for treating juvenile rheumatoid arthritis in children age two and older. For children weighing between 22 and 55 pounds, the recommended celecoxib dose is 50 mg twice daily. For children weighing 55 pounds or more, the recommended dosage is 100 mg twice daily.
Ankylosing Spondylitis (AS)
The recommended starting dosage of celecoxib for most people with ankylosing spondylitis is 200 mg a day -- either as a single dose or 100 mg twice day. After several weeks, if pain is still present, your healthcare provider may increase your dose to 400 mg per day. If pain still does not improve, your healthcare provider may recommend other options for pain relief.
Acute Pain or Painful Menstruation
When treating acute pain or painful menstruation, celecoxib dosing guidelines recommend 400 mg, followed by another 200 mg (if needed) on the first day. After the first day, the recommended dose is 200 mg, twice a day, as needed.

General Information on Your Dosage of Celecoxib

People taking celecoxib should consider the following information:
  • Celecoxib can be taken at any time during the day. However, the dose should be taken at the same time each day to maintain an even level in your system.


  • Your dosage can be taken with or without food. However, people taking 400 mg of celecoxib twice daily should take it with food.
  • Do not break, chew, or crush the capsules. If necessary, you may open the capsules and sprinkle the contents on a spoonful of cool or room-temperature applesauce. This should be swallowed immediately and followed with water, although the medication is stable in the applesauce for up to six hours under refrigeration.
  • For celecoxib to work properly, you have to take it as prescribed. The medication will not work if you stop taking it.
  • It is important to take the lowest effective celecoxib dose for the least amount of time in order to treat your condition. This will decrease the risk of serious side effects.
  • If you are unsure about your celecoxib dosage or anything else related to the medication, talk to your doctor, nurse, or pharmacist. Do not stop taking celecoxib without first discussing it with your healthcare provider.
Alternative Therapies for Pain Management

Celecoxib (Celebrex)

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