Butrans Drug Interactions
Medications That Cause Drowsiness
Butrans causes significant drowsiness. Taking it with other medications that cause drowsiness may lead to serious side effects, such as extreme sedation, low blood pressure, confusion, and serious breathing problems. Check with your healthcare provider before using Butrans with other medications that can cause drowsiness.
Monoamine Oxidase Inhibitors (MAOIs)
Combining Butrans with an MAOI may cause serious problems. Do not use Butrans if you have taken an MAOI within the past 14 days.
At high doses, Butrans increases the risk for a potentially dangerous change in heart rhythm known as QT prolongation. Certain other medications also increase this risk. Check with your healthcare provider before using these drugs together.