Precautions and Warnings With Buprenorphine

If you have low blood pressure, liver disease, kidney disease, or gallbladder problems, tell your healthcare provider before using buprenorphine. Other precautions and warnings to keep in mind involve avoiding heat on the skin if you are using buprenorphine patches and being aware that this drug has abuse potential. If you are allergic to any of the ingredients in this product, do not use it.

What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to taking buprenorphine (Buprenex®, Butrans®, Subutex®, Suboxone®) if you have:
 
  • A history of stroke
  • A history of seizures
  • Problems urinating
  • Low blood pressure (hypotension)
  • Gallbladder or pancreas disease
  • A history of drug or alcohol dependence or abuse
  • A history of breathing problems, asthma, chronic obstructive pulmonary disease (COPD), or other lung disease
  • Heart disease of any kind
  • An irregular heart rhythm (arrhythmia)
  • A very slow heart rate (bradycardia)
  • A head injury, brain tumor, or increased pressure around the brain
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any allergies, including to foods, dyes, or preservatives.
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Also, let your healthcare provider know if you are:
 
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
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Make sure to tell your healthcare provider about any medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
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Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
 
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