Buprenex Warnings and Precautions

Before receiving Buprenex, there are many precautions to be aware of, including warnings on who should not use the drug and possible side effects that may occur. For example, this injection could cause serious reactions (such as potentially life-threatening breathing problems) for some people and may not be safe for use in women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to receiving Buprenex® (buprenorphine injection) if you have:
 
  • A history of drug or alcohol dependence or abuse
  • A history of breathing problems, asthma, chronic obstructive pulmonary disease (COPD), or any other lung disease
  • Heart disease of any kind
  • An irregular heart rhythm (arrhythmia)
  • A very slow heart rate (bradycardia)
  • A head injury, brain tumor, or increased pressure around the brain
  • A history of strokes
  • A history of seizures
  • Problems urinating
  • Low blood pressure (hypotension)
  • Gallbladder or pancreas disease
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
 
Make sure to tell your healthcare provider about any medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
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Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
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