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Avinza Warnings and Precautions

Specific Precautions and Warnings for Avinza

Warnings and precautions to be aware of prior to taking Avinza include the following:
  • Avinza contains tiny extended-release beads. Do not dissolve, chew, or crush the capsules, as this could release too much medication, causing a potentially fatal overdose.
  • You must not consume any alcohol while taking Avinza, as alcohol can cause the extended-release beads to release too much morphine too quickly, possibly causing a fatal overdose. This includes alcoholic beverages, as well as alcohol in foods and medications.
  • The maximum Avinza dosage is 1600 mg total per day. Taking more than 1600 mg per day could cause kidney damage due to the fumaric acid content in Avinza.
  • Avinza is a narcotic medication with significant potential for abuse. It is not a good choice for people who have a history of alcohol or drug abuse (see Avinza Abuse). Do not take the drug more frequently, longer, or at a higher dose than prescribed. If you feel you may be developing a problem with Avinza abuse, please seek help from your healthcare provider.
  • The medication can cause problems in people with head injuries or high intracranial pressure. Avinza should only be used with extreme caution in such circumstances.
  • Avinza can cause slow and irregular breathing. In severe situations, this may be life-threatening. This may be especially dangerous in people with lung problems.
  • Avinza can cause a decrease in blood pressure, which can be especially dangerous if you already have low blood pressure.
  • Narcotics such as Avinza are likely to cause constipation. This side effect does not go away as you continue to take the drug. Usually, laxatives are necessary to treat and prevent constipation due to Avinza (see Avinza and Constipation). Let your healthcare provider know if you develop severe constipation, as this could be a sign of an intestinal blockage.
  • Avinza can interfere with the diagnosis of many conditions that cause severe abdominal (stomach) pain.
  • Like any other narcotic, Avinza can cause dizziness and drowsiness, and may increase the risk of falls in elderly people.
  • Do not drive or operate heavy machinery until you know how Avinza affects you. Your reflexes and reaction times may be significantly affected, even if you feel fine.
  • Check with your healthcare provider before taking the drug if you have hypothyroidism, Addison's disease, an enlarged prostate, epilepsy, gallbladder problems, pancreatic disease, or kidney disease, as Avinza may not be the best choice for you.
  • Avinza can potentially interact with several other medications (see Avinza Drug Interactions).
  • Avinza is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Avinza and Pregnancy).
  • Avinza passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Avinza and Breastfeeding).
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Avinza Medication Information

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